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CORE Symposium 2026 Philadelphia


The half-day event where clin ops leaders come to solve the problems other events only talk about. Real challenges. Real collaboration. Zero ballrooms.

SEPT 21, 2026, 12-5 pm | CITIZENS BANK PARK, PHILADELPHIA ⚾

CORE Symposium Fenway Park
CORE Symposium Fenway Park
CORE Symposium Fenway Park
CORE Symposium Fenway Park
CORE Symposium Fenway Park
CORE Symposium Fenway Park
CORE Symposium Fenway Park
CORE Symposium Fenway Park
CORE Symposium Fenway Park
CORE Symposium Fenway Park
CORE Symposium Fenway Park
CORE Symposium Fenway Park

What is CORE Symposium?

CORE (Clinical Operations, Recruitment, and Engagement) is ProofPilot's biannual invite-only, half-day gathering for pharma and biotech leaders who are done with windowless ballrooms, exhibit floors, and sales pitches.

CORE ditches the standard playbook for an interactive format designed to produce real solutions and next steps, not polite applause.

And it all happens in a memorable venue with unexpected delights to shake up your perspective.

Who Attends CORE?

The CORE Symposium is tailored to clin ops leaders, particularly trial sponsors, committed to reimagining the clinical trial experience. Check out the companies who attended our Spring 2026 event in Boston.

Acumen
Alexion
Alkermes
Alnylam
AOBiome
Axonis
BeOne
Biogen
BI (1)
Cellarity
Corbus
Cullinan
Cyclo
Daiichi
Deciphera
Disc
Eli Lilly
Fulcrum
Harbinger Health
Invivyd
Javara
Kymera
Liquidia
Merck
MetaVia
Novartis
Pelage
Prothena
Raven
Ratio Tx
RealTime
Repertoire
TG Tx
Transcode
Veristat
Vertex
Yarrow

Not just another industry conference.

Here's what makes CORE different from your standard clin ops event.


Actionable agenda, candid talk

CORE’s interactive, hands-on design is built for real learning and action, not inspiration. CORE is about intimate, unfiltered conversations about the reality of clinical operations.

Change of scenery with a fresh format

No windowless ballrooms. No booths. CORE breaks out of the norm to offer more connection, fresh energy, and openness to new and unexpected ideas.

Built for doers, not talkers

We’re not here to talk or fantasize about the future. CORE is for leaders who are looking to walk off the field with ready-to-use tactics they created with their own peers.


80+ leaders

every seat intentional

40+ companies

across pharma and biotech

0 booths & ballrooms

trade the ballroom for the ballpark

What we're talking about in Philadelphia

The September 2026 program zeroes in on the limitations, pain points, and downstream impacts of the models we use to forecast and track enrollment.

Philadelphia agenda highlights:

  • Hear from your peers on why forecasts break and what interventions actually work

  • Work alongside peers in a hands-on forecasting workshop to empower real progress for your own study team

  • Explore the tools improving forecasting accuracy and optimizing enrollment

  • Celebrate real change during the Change Agent Awards

Full Agenda | Click Any Item to Expand

12:00 • Doors open + networking lunch
Join us for a casual networking lunch before we dive into the deep stuff. Also head outside for a photo in front of the field and to see your name on the Citizens Bank Park scoreboard.
1:15 • Planning and forecasting panel discussion

From Algebra to Actionable: Rethinking Clinical Trial Enrollment Forecasting

Hear from leaders at Boehringer Ingelheim, Acadia Pharmaceuticals, and Veristat about why the traditional approach to enrollment forecasting—target divided by sites and months—is a naive formula that sets trials up to fail before FPI. This panel unpacks cycle times versus enrollment curves, where benchmarks help versus mislead, and how to diagnose risk early enough to know which interventions actually move the needle. Walk away with a sharper framework for evaluating your own forecasting practice and a clearer eye for what separates trials that hit their targets from those that don't.

2:00 • Hands-on forecasting and diagnostics workshop

Workshop: The Cost of Getting it Wrong (Exercises 1 & 2)

The first two exercises of CORE's hands-on enrollment forecasting and diagnostics workshop will focus on identifying the downstream effects of enrollment forecasting failures, and constructing a forecast from benchmark data.

Attendees will break out into teams and draw on real-world experience to collaborate and problem-solve during both exercises.

3:00 • Networking & refreshment break
Grab some refreshments, stretch your legs, and chat with your peers as you digest the insights from the first half of the event.
3:30 • Hands-on workshop cont'd

Workshop: The Cost of Getting it Wrong (Exercise 3)

In the final exercise, teams will diagnose an off-track enrollment scenario and recommend a corrective action plan.

4:15 • Workshop debrief + open discussion
Discuss insights, questions, and aha moments from the workshop exercises with the full room of attendees. Simply listen and observe, or share your own thoughts and questions with the room.
4:45 • Change Agent Award presentation
We'll reveal our Change Agent Award recipient and celebrate one special person from the industry who has driven real, positive change in their organization.
5:00 • Reception, tour, and batting cages
CORE isn't all work and no play. Stick around for appetizers and drinks, a quick stadium tour, and—yes, you read that right—a stop at the batting cages!

Who You'll Be Learning From

The CORE stage has featured leaders from across the pharma and biotech landscape. We've hosted speakers from AstraZeneca, Alnylam, Biogen, Boehringer Ingelheim, Invivyd, Pelage Pharmaceuticals, Pfizer, Takeda, Tris Pharma, and more.  

Check back soon for our 2026 CORE Philadelphia speaker announcements.

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Change Agent of the Year

Each CORE Symposium, we recognize one pharma and biotech professional who has implemented and scaled a new mode of working to improve clinical operations for their organization. The award is presented live on the event stage.

Previous winners:

2026 (Boston) · Rachel Ovens, Boehringer Ingelheim
2025 (Boston) · Jenn Curry, Biogen

Ready to experience CORE?

Fill out the form to request your seat!

Please note that spaces are limited and reserved for professionals at Pharma and Biotech.

 

Request your seat!

THIS IS HOW WE ROLL

Clinical trials test grit. We bring the fun.

At industry events, we’ve left our mark with fun panels like The Dating Game and Pharma Feud, unexpected friends like T-rexes and enormous robots, and we’ve even broken a world record right on the conference floor!

Sponsorship Opportunities

Interested in CORE Symposium sponsorship opportunities? Contact us to learn how to get involved with this one-of-a-kind event.

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